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Puromycin Dihydrochloride, 500 MG

Price$ 415.00
You Save$ 224585.00
  • SKU: P-1033-500MG
  • Pack Size: 500 MG
Quantity
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58-58-2

544.43 Da

C22H29N7O5 • 2HCl

Soluble in water (50 mg/mL), ethanol (~1 mg/mL), DMSO (~13 mg/mL), DMF (~14 mg/mL), and PBS, pH 72 (~10 mg/mL)

-20°C


Description

Puromycin Dihydrochloride is an aminoglycoside antibiotic that is isolated from Streptomyces alboniger. Puromycin acts as a protein synthesis inhibitor by incorporating itself into a polypetide chain that has been growing, causing it to prematurely terminate. Puromycin’s primary application is as a gene-selection antibiotic with an important role in gene-editing via CRISPR/Cas9.

This puromycin reagent, which is in the form of hydrochloride salt, has antineoplastic, antitrypanosomal, and antimicrobial properties. It is important to keep Puromycin Dihydrochloride stored in a tightly closed container in a well-ventilated and dry area.

 

Applications

• Selective antibiotic agent for cell culture systems, selection of mammalian cell lines
• Protein synthesis inhibitor
• Studies of regulatory mechanisms which control specific gene functions during cell differentiation
• Can be used for specific types of cancer therapy

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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