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Staurosporine, 250 UG

Price$ 45.00
  • SKU: S-1016-250UG
  • Pack Size: 250 UG
Quantity
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Total price: $ 826.43

This item: Staurosporine, 250 UG $ 45.00

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62996-74-1

466.5 Da

C28H26N4O3

DMSO (50 mg/mL) or ethanol (2 mg/mL, warm).

+4°C


Description

Staurosporine is a cell-permeable protein kinase inhibitor that acts by blocking interaction with the ATP binding site. It mainly inhibits protein kinase C (PKC) but most other kinases, including tyrosine kinases. It has some antifungal properties.

It has been reported that Staurosporine promotes apoptosis in various cell types by triggering both the morphological changes and intranucleosomal DNA fragmentation and by caspase-dependent and -independent ways. In addition, it has been reported that the kinase inhibitor is related to signaling pathway.

 

Applications

• Apoptosis inducer

• Antibiotic

• Protein kinase inhibitor

 

References

“Induction of a Common Pathway of Apoptosis by Staurosporine”

“Staurosporine-Induced Neuronal Apoptosis”

“Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms”

“Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2.”

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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