Soluble in ethanol, methanol, DMF and DMSO.
Tenellin is a yellow fungal metabolite produced by species of the genus Beauveria which belongs to the rare 4-hydroxypyridone class including a dienone side chain. The fungus causes white muscardine disease in silkworms.
It has been reported that tenellin plays an important role in iron homeostasis in the ferricrocin-deficient Beauveria bassiana. It downregulates the toxicity of iron-generated reactive oxygen species by working as an iron chelator in ferricrocin-deficient mutants Beauveria bassiana.
It suppresses Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes and is cytotoxic to Sf9 and Sf21 insect cells.
• Biocontrol agent
• Iron chelator in ferricrocin-deficient mutant Beauveria bassiana
Not for human therapeutic use or for medicinal purposes. For research applications only.
Research or further manufacturing use only, not for food or drug use.