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Tenellin, 1 MG

Price$ 361.82
  • SKU: T-2601-1MG
  • Pack Size: 1 MG
Quantity
-
+

53823-15-7

369.4

C21H23NO5

Soluble in ethanol, methanol, DMF and DMSO.

-20°C


Description

Tenellin is a yellow fungal metabolite produced by species of the genus Beauveria which belongs to the rare 4-hydroxypyridone class including a dienone side chain. The fungus causes white muscardine disease in silkworms.

It has been reported that tenellin plays an important role in iron homeostasis in the ferricrocin-deficient Beauveria bassiana. It downregulates the toxicity of iron-generated reactive oxygen species by working as an iron chelator in ferricrocin-deficient mutants Beauveria bassiana.

It suppresses Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes and is cytotoxic to Sf9 and Sf21 insect cells.

 

Applications

• Biocontrol agent

• Iron chelator in ferricrocin-deficient mutant Beauveria bassiana

  

References

“Bio-Pesticides: Application and Possible Mechanism of Action”

“Tenellin acts as an iron chelator to prevent iron-generated reactive oxygen species toxicity in the entomopathogenic fungus Beauveria bassiana”

“BIOACTIVE METABOLITES OF ENTOMOPATHOGENIC FUNGI Beauveria bassiana”

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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