53823-15-7
369.4
C21H23NO5
Soluble in ethanol, methanol, DMF and DMSO.
-20°C
Description
Tenellin is a yellow fungal metabolite produced by species of the genus Beauveria which belongs to the rare 4-hydroxypyridone class including a dienone side chain. The fungus causes white muscardine disease in silkworms.
It has been reported that tenellin plays an important role in iron homeostasis in the ferricrocin-deficient Beauveria bassiana. It downregulates the toxicity of iron-generated reactive oxygen species by working as an iron chelator in ferricrocin-deficient mutants Beauveria bassiana.
It suppresses Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes and is cytotoxic to Sf9 and Sf21 insect cells.
Applications
• Biocontrol agent
• Iron chelator in ferricrocin-deficient mutant Beauveria bassiana
References
• “Bio-Pesticides: Application and Possible Mechanism of Action”
• “BIOACTIVE METABOLITES OF ENTOMOPATHOGENIC FUNGI Beauveria bassiana”
Not for human therapeutic use or for medicinal purposes. For research applications only.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
