33956-61-5
793 Da
C44H72O12
Soluble in ethanol, water (limited), methanol, DMF, and DMSO
-20°C
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Description
Tetranactin is a macrotetrolide produced by Streptomyces aureus. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. It is demonstrated to inhibit synthesis and release of IL-2 by mitogen-activated lymphocytes and it shows immunosuppressive effects by affecting intracellular cation concentrations.
It has antibacterial, insecticidal and mitogenic activities. The antibiotic suppresses the growth of Gram-positive bacteria and some phytopathogenic fungi in vitro at low concentrations.
Tetranactin ionophore has limited water solubility but is soluble in most organic solvents.
Applications
• Monovalent cation ionophore
• Antibiotic
• Immunosuppressive agent
References
• “Tetranactin, A New Miticidal Antibiotic”
• “Immunosuppressive and anti-proliferative effects of a macrotetrolide antibiotic, tetranactin”
Not for human therapeutic use or for medicinal purposes. For research applications only.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
