Soluble in Dichloromethane or Methanol, DMSO (0.5%). 1 mg/ml of Thiolutin in DMSO gives a clean orange solution.
Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability.
Research or further manufacturing use only, not for food or drug use.