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L-Quisqualic Acid, 1 MG

Price$ 53.99
  • SKU: Q-1000-1MG
  • Pack Size: 1 MG
Quantity
-
+

52809-07-01

189.13 Da

C5H7N3O5

1 eq. NaOH to 100mM, water to 10mM

+4°C


Description

L-Quisqualic Acid is one of the most potent AMPA receptor agonists, causing excitotoxicity -- a process in which nerve cells are killed or damaged due to the overstimulation of neurotransmitters. It is also believed to mimic the excitatory neurotransmitter L-glutamic acid, which is studied in relation to insect neuromuscular function and the mammalian central nervous system.

Applications

Commonly used in neuroscience to deliberately kill brain and/or spinal cord neurons, L-Quisqualic Acid is also used to sensitize neurons to depolarization within the hippocampus (known as the "quis effect") -- which is the movement of a cell membrane's potential, making it slightly more positive.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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