8-bromo-cyclic GMP (sodium salt); 8-bromo-cGMP; 8- bromo Guanosine 3’,5’-cyclic monophosphate
PBS (pH 7.2): 10 mg/mL
8-Br-cGMP is a cell-permeable cGMP analog having greater resistance to hydrolysis by phosphodiesterases than cGMP. Activates cGMP-dependent protein kinase (PKG), slows or inhibits the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine. It inhibits thrombin stimulated arachidonic acid release in human platelets.
Research or further manufacturing use only, not for food or drug use.