75607-67-9
365.21
C10H13FN5O7P
Soluble in DMSO or H2O (5 mg/ml)
-20°C
A chemotherapy drug used in the treatment of hematological malignancies. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase-, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.