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CK-666, 5 MG

Price$ 95.01
  • SKU: C-2917-5MG
  • Pack Size: 5 MG
Quantity
-
+

442633-00-3

296.3

C18H17FN2O

May be dissolved in DMSO (45 mg/ml); or ethanol (30 mg/ml)

-20°C


Description

CK-666 is a potent, selective and reversible inhibitor of actin assembly mediated by actin related protein Arp2/3 complex. It binds to Arp2/3 complex, stabilizes the inactive state of the complex and prevents movement into active conformation. CK-666 attenuates blood-brain barrier (BBB) dysfunction induced by methamphetamine. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in both normal physiology and pathophysiology.

 

Application

• CK-666 may be used to study Arp2/3-mediated structual changes in cells.

• IC50 = 4 µM for human ARP2/3

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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