Slightly soluble in methanol or ethanol. Avoid DMSO.
Cell permeable, very sensitive and specific chemiluminescence probe of the superoxide anion and peroxynitrite. When oxidized by oxygen it illuminates blue light at 446nm when Ca2+ binds to the complex. Coelenterazine was originally isolated from Aequorea victoria. Many of the coelenterazine analogs possess properties different from those of native coelenterazine. These include half-life, aequorin regeneration rate, luminescence capacity, emission maximum and membrane permeability.
• gene reporter assays
• whole animal assays
• biochemical assays
• live-cell assays for the detection of calciem ions
Research or further manufacturing use only, not for food or drug use.