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SMER28, 5 MG

Price$ 22.14
  • SKU: S-2436-5MG
  • Pack Size: 5 MG
Quantity
-
+

307538-42-7

264.12

C11H10BrN3

DMSO (~8 mg/ml) or EtOH (~ 2 mg/ml)

-20°C


Acts as a positive regulator of autophagy, acting via mTOR-independent mechanism. SMER28 increases autophagosome synthesis and enhances the clearance of model autophagy substrates such as A53T a-synuclein and mutant huntingtin fragments. It is also protective in Drosophila model of Huntington's Disease (HD). Maybe a useful lead compound for the development of new therapeutics for neurodegenerative diseases. Induces the release of articular cartilage vesicles from healthy articular chondrocytes in a dose- and time-dependent manner.  Promotes reprogramming of fibroblasts to neural stem-like cells. Cell permeable.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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