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Amlodipine, 100 MG

Price$ 43.19
  • SKU: A-2537-100MG
  • Pack Size: 100 MG
Quantity
-
+

88150-42-9

408.879

C20H25ClN2O5

Soluble in DMSO (25 mg/mL), ethanol (25 mg/mL), water (75.3 mg/mL), DMF (25 mg/mL), acetone, chloroform, ethyl acetate, and methanol.

Room Temperature


Description

Amlodipine is a calcium channel blocker with a demonstrated affinity for cellular membranes. When administered, it inhibits calcium influx in vascular muscle tissues. While it is classified as a dihydropyridine calcium blocker, there is evidence to suggest that amlodipine acts on dihydropyridine and nondihydropyridine sites alike.

Applications

In clinical medical practice, amlodipine is widely prescribed as an antihypertensive drug. As a calcium channel blocker, amlodipine has the effect of dilating arteries, thus allowing for less constricted blood flow. This compound may also be prescribed as a preventative drug for attacks of angina-related chest pain. Clinical trials have also investigated the effect of amlodipine on microvascular function. In more recent research, amlodipine has been paired with other calcium channel blockers in experimental two-drug combinations. Pairings of amlodipine with perindopril and hydrochlorothiazide have both been shown to be effective in significantly reducing blood pressure in sub-Saharan African populations.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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