13408-56-5
464.6 Da
C27H44O6
Soluble in acetic acid, 100% ethanol, methanol or DMSO.
-20°C
Description
Ponasterone A is an off-white powder that is part of the ecdysteroid family. It has properties that are similar to muristerone A. It is a steroid hormone in insects that plays a role in regulating metamorphosis. Ponasterone A is a powerful gene expression regulator that rapidly activates and deactivates reporter genes in cells and transgenic organisms.
Ponasterone A is an ecdysone A analog and can function as an economical and reliable substitute for muristerone A. It acts as an ecdysone-inducible mammalian expression system inducer. It is a very bioactive ligand in vivo, displaying continual release and transgene expression.
Applications
• Regulation of gene expression
• Can increase cell number at G1 phase while also inhibiting cell growth
• Enables reporter genes to be turned off and on rapidly
• Researchers have used Ponasterone A for studies on iron-related conditions, various cancers in humans, and neurodegenerative diseases
Not for human therapeutic use or for medicinal purposes. For research applications only.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
