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Vildagliptin, 20 MG

Price$ 166.05
  • SKU: V-2421-20MG
  • Pack Size: 20 MG
Quantity
-
+

274901-16-5

303.4

C17H25N3O2

May be dissolved in DMSO (45 mg/ml); or DMF (20 mg/ml); or ethanol (20 mg/ml)

-20°C


A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that cleaves glucagon-like peptide 1 (GLP-1)1. Delaying the degradation of GLP-1 extends the action of insulin and suppresses the release of glucagon which results in reduction in elevated blood glucose levels (hyperglycemia)2. Ameliorates cognitive deficits in streptozotocin-induced Alzheimers disease model3. Displays protective effects on b-cells by inhibition of ER stress in a mouse model4. Clinically useful antidiabetic agent.

Vildagliptin increases β cell mass by not only directly affecting cell kinetics but also by indirectly reducing cell apoptosis, oxidative stress and endoplasmic reticulum stress in diabetic mice.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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