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DMPO, 1 G

Price$ 168.85
  • SKU: D-2449-1GM
  • Pack Size: 1 G
Quantity
-
+

3317-61-1

113.159

C6H11NO

May be dissolved in DMSO (25 mg/ml); or ethanol (25mg/ml)

-20°C


Description

5,5-Dimethyl-1-pyrroline N-oxide (DMPO) is commonly used as a cell-permeable, hydrophilic spin trap agent for studies of superoxide, S-, O-, C- and N- centered free radicals in electron paramagnetic resonance (EPR). This agent is water-soluble and able to penetrate lipid bilayers.

It has demonstrated neuroprotective properties. The presence of DMPO while incubation of lymphocytes decreases DNA damage by NiCl. It is reported that the recovery of heart function is improved in DMPO-treated hearts in a rat model.

 

Applications

• Study of free radicals

• Detection of superoxide

 

References

• “Heart protection and radical trapping by DMPO during reperfusion in isolated working rat hearts”

• “ESR measurement of rapid penetration of DMPO and DEPMPO spin traps through lipid bilayer membranes”

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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