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Dithiothreitol [DTT], 5 G

Price$ 39.50
  • SKU: C-1029-5GM
  • Pack Size: 5 G
Quantity
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Frequently Bought Together

Total price: $ 193.92

This item: Dithiothreitol [DTT], 5 G $ 39.50

Proteinase K (Recombinant), Molecular/PCR Grade, 100 MG $ 79.42

EGTA 0.5M Solution pH 8.0, 50 ML $ 75.00

DTT; DL-Dithiothreitol; Cleland’s reagent; 1,4-Dithio-DLthreitol;threo-1,4-Dimercapto-2,3-butanediol; 1,4- bis(sulfanyl)butane-2,3-diol

3483-12-3

154.25

C4H10O2S2

Water

2-8°C


Description:

Dithiothreitol (DTT), is a small-molecule redox reagent, known as Cleland's reagent, that forms a six-member ring with an internal disulfide bond. It has a redox potential of -0.33 V at pH 7. The reduction of typical disulfide bond proceeds by two sequential thiol-disulfide exchange reactions.
 

DTT is effective in buffers to reduce protein disulfide bonds prior to SDS-PAGE. It can protect protein sulfhydryls and restore enzyme activity lost by oxidation.

 

Applications:

  • For reducing or "deprotecting" agent for thiolated DNA
  • For reducing disulfide bonds of proteins
  • Used as an oxidizing agent
  • Used as a component of medium for the demembranation and reactivation of spermatozoa
  • Used to prevent intramolecular and intermolecular disulfide bonds from forming between cysteine residues of proteins
 

Additional Reading from AG Scientific:

 

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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