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Dithiothreitol [DTT], 5 G

Price$ 35.62
  • SKU: C-1029-5GM
  • Pack Size: 5 G
Quantity
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Frequently Bought Together

Total price: $ 190.04

This item: Dithiothreitol [DTT], 5 G $ 35.62

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EGTA 0.5M Solution pH 8.0, 50 ML $ 75.00

3483-12-3

154.2

C4H10O2S2

10% solution in water. Clear and colorless

2-8°C


Description

Dithiothreitol (DTT), is a small-molecule redox reagent, known as Cleland's reagent, that forms a six-member ring with an internal disulfide bond. It has a redox potential of -0.33 V at pH 7. The reduction of typical disulfide bond proceeds by two sequential thiol-disulfide exchange reactions.

DTT is effective in buffers to reduce protein disulfide bonds prior to SDS-PAGE. It can protect protein sulfhydryls and restore enzyme activity lost by oxidation.

 

Applications

• For reducing or "deprotecting" agent for thiolated DNA
• For reducing disulfide bonds of proteins
• Used as an oxidizing agent
• Used as a component of medium for the demembranation and reactivation of spermatozoa
• Used to prevent intramolecular and intermolecular disulfide bonds from forming between cysteine residues of proteins

 

Additional Reading from AG Scientific

DTT (Dithiothreitol): Frequently Asked Questions

DTT (Dithiothreitol): Applications You Must Know

TCEP HCl vs. DTT: Preferred Reducing Agents

Download Brochure: Reducing Agents

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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