(±)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)- dione
50-35-1
258.2
C13H10N2O4
DMSO
Room Temperature
Thalidomide binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A inhibiting ligase activity. Inhibits TNFα synthesis and FGF-induced angiogenesis. Cell permeable.
Caution: Teratogenic. Pregnant women should avoid using this compound.
0.1 lbs
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