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Podophyllotoxin, 100MG

Price$ 52.59
  • SKU: P-3301-100MG
  • Pack Size: 100MG
Quantity
-
+

518-28-5

414.4

C22H22O8

Soluble in chloroform, acetone, ethyl acetate or ethanol. Insoluble in water.

-20°C


Description

Podophyllotoxin is a potent microtubule assembly inhibitor. It has antineoplastic and apoptotic properties so it can be used as an anticancer reagent.

The toxin binds to topoisomerase II during the late S and early G2 stage. It interferes with tubulin polymerization and thus ultimately inhibits mitosis.

Podophyllotoxin derivatives such as etoposide, etopophos, and teniposide have been successfully utilized in the treatment of a variety of malignant conditions and have shown potent antiviral, immunosuppressive and cytotoxic properties as well.

 

Applications

• Microtubule assembly inhibitor

• Anticancer agent

• Apoptosis inducer

• DNA topoisomerase II inhibitor

• Antiviral and anthelmintic agent

 

References

• “Podophyllotoxin”

“Podophyllotoxin: Current Perspectives”

“Endophyte Fungal Isolates from Podophyllum peltatum Produce Podophyllotoxin”

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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