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FK-866, 1 MG

Price$ 75.96
  • SKU: F-2328-1MG
  • Pack Size: 1 MG
Quantity
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+

658084-64-1

391.51

C24H29N3O2

Soluble in DMSO (30 mg/ml) and Ethanol

-20°C


Cell-permeable. FK-866 is a highly specific non-competitive inhibitor of Nicotinamide phosphoribosyltransferase (NAMPT) (K = 0.4 nM), causing gradual NAD+ depletion. NAMPT functions as an intra-cellular and extra-cellular NAD biosynthetic enzyme that is important for regulating metabolism and stress resistance through sirtuins and other NAD-consuming regulators. NAD+ depletion by FK-866 directs delayed cell death by apoptosis in Hep-G2 human liver carcinoma cells

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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