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FK-866, 5 MG

Price$ 156.75
  • SKU: F-2328-5MG
  • Pack Size: 5 MG
Quantity
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+

APO-866; ​Daporinad; K 22.175

658084-64-1

391.5

C24H29N3O2

DMF, DMSO, Ethanol

-20°C


FK-866 is a cell-permeable, highly specific, non-competitive inhibitor of Nicotinamide phosphoribosyltransferase (NAMPT) (K = 0.4 nM), causing gradual NAD+ depletion.

NAMPT functions as an intra-cellular and extra-cellular NAD biosynthetic enzyme that is important for regulating metabolism and stress resistance through sirtuins and other NAD-consuming regulators. NAD+ depletion by FK-866 directs delayed cell death by apoptosis in Hep-G2 human liver carcinoma cells.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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