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TNF-α Inhibitor, 5 MG

Price$ 271.36
  • SKU: T-1252-5MG
  • Pack Size: 5 MG
Quantity
-
+

1049741-03-8

629.6

C32H32F3N3O2HCI •1/2H2O

DMSO

-20°C


A cell-permeable indoly-chromenone compound that rapidly inactivates TNF-α by non-covalently binding to the TNF-α  trimer and promotin sbunit dissociation and preventing TNF-α  binding to its receptor (IC50 = 22 μM).  Shown to selectively inhibit TNF-α, but not IL-1β-induced IkB-α degradation in HeLa cells (IC50 = 4.6 μM).

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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