DMSO (50 mM)
A Tankyrase (TNKS) inhibitor (IC= 110 nM for TNKS1 and 4 nM for TNKS2). Antagonizes wnt signaling via stimulation ofcatenin degradation and stabilization of axin. Inhibits proliferation of the-catenin-dependent colon carcinoma cell line DLD-1.
Research or further manufacturing use only, not for food or drug use.