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1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane

Price$ 0.00
  • SKU: C-2275
  • Pack Size: Curcuma longa (High Purity)
Quantity
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1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane

458-37-7

368.38

C21H20O6

DMSO (25 mg/ml) or EtOH (10 mg/ml)

-20°C


Cell-permeable. An antioxidant and dual inhibitor of 5-lipoxygenase (IC= 8 M)and cyclooxygenase (COX) (IC= 52 M). Also inhibits glutathione S-transferase,induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Also shown to be a p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, inhibiting the acetylation of histones H3 and H4 with an ICof ~25 M. Does not affect p300/CREB binding protein-associated factor (PCAF).

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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