Soluble in methanol (1mg/ml); insoluble in water
Synonym: 4-[(2,4-DIMETHOXY-6-METHYLBENZOYL)OXY]-2-HYDROXY-6-METHYL-BENZOIC ACID 4-CARBOXY-3-HYDROXY-5-METHYLPHENYL ESTER
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC=17.5 M) and Raji cells (IC=2.8 M). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Research or further manufacturing use only, not for food or drug use.