DMSO (25 mM)
Cell-permeable. A reversible, p300/CBP (CREB-binding protein) histone acetyltransferase (HAT) inhibitor (K = 400 nM). Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (10%). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.
Research or further manufacturing use only, not for food or drug use.