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MS-275, HDAC inhibitor, 25 MG

Price$ 180.84
  • SKU: M-3331-25MG
  • Pack Size: 25 MG
Quantity
-
+

209783-80-2

376.42

C21H20N4O3

Soluble in DMSO (up to 25 mg/ml).

-20°C


MS-275 (209783-80-2) is a potent HDAC inhibitor. Selective for HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM) and HDAC8 (IC50 100 μM). In vivo, MS-275, has been shown to inhibit tumor growth via induction of the tumor supressors p21WAF1/CIP1 and gelsolin and to block cell proliferation in a variety of cancer cell lines. MS-275 has also shown significant anti-rheumatic activity in rat and mouse arthritis models.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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