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Price$ 271.36
  • SKU: T-2472-1MG
  • Pack Size: 1 MG



DMSO (~90 mg/ml) or Water (~ 4mg/ml) or 2% TWEEN-80/water (~2 mg/ml) or 30% PEG (avg. MW = 400 g/mol)/50 mM phosphate buffer (pH = 2.25) (25 mg/ml) (heating is required to initially dissolve the compound).


Cell-permeable. A potent and selective HDAC6 (histone deacetylase 6) inhibitor. Displays 1093-fold selectivity over HDAC1 (ICvalues of 15 nM for HDAC6 vs 16.4 M for HDAC1). Tubastatin A was substantially more selective than the known HDAC6 inhibitor Tubacin at all isozymes except HDAC8. In addition, it displayed over 1000-fold selectivity against all HDAC isoforms excluding HDAC8, where it displayed 54-fold selectivity. Tubastatin A displayed dose-dependent protection against HCA (homocysteic acid)-induced neuronal cell death starting at 5 M with near complete protection at 10 M.

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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