DMSO (20 mg/ml) or Ethanol (2 mg/ml)
A potent and selective inhibitor of the TGF- 1 receptor ALK5 (IC= 94 nM). It inhibits ALK4 only at higher concentrations (IC= 140 nM). Suppresses renewal in embryonic and induced pluripotent stem (iPS) cells and promotes their differentiation through its effect on Smad signaling pathway.
Research or further manufacturing use only, not for food or drug use.