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Isozyme-Selective-Akt Inhibitor, 1 MG

Price$ 150.76
  • SKU: A-1714-1MG
  • Pack Size: 1 MG
Quantity
-
+

612847-09-3

551.65

C34H29N7O

Soluble in DMSO

-20°C


Synonym: 1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one; Akti-1/2

Description:
Isozyme-selective-Akt inhibitor is a cell-permeable, potent and selective inhibitor of Akt1/Akt2 activity (IC = 58 nM (Akt1), 210 nM (Akt2) and 2.12 M (Akt3) in vitro kinase assays. The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akt's, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50 M).

0.1 lbs



Research or further manufacturing use only, not for food or drug use.