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Isozyme-Selective-Akt Inhibitor, 1 MG

Price$ 161.25
  • SKU: A-1714-1MG
  • Pack Size: 1 MG




Soluble in DMSO


Synonym: 1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one; Akti-1/2

Isozyme-selective-Akt inhibitor is a cell-permeable, potent and selective inhibitor of Akt1/Akt2 activity (IC = 58 nM (Akt1), 210 nM (Akt2) and 2.12 M (Akt3) in vitro kinase assays. The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akt's, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50 M).

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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