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Price$ 199.00
  • SKU: A-2189-5MG
  • Pack Size: 5 MG
Quantity
-
+

587871-26-9

395.49

C21H17NO3S2

DMSO (100 mM) and Ethanol (50 mM)

-20°C


Synonym: 2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one

Description:
A potent, selective and ATP-competitive inhibitor of ATM Kinase (K = 2.2 nM; IC= 13 nM). Inhibits DNA-PK, mTOR, PI 3-K, PI 4-K, and ATR at much higher concentrations (IC= 2500, 9300, 16600, 100000 and 100000 nM, respectively). KU-55933 inhibits cancer cell proliferation by inducing G(1) cell-cycle arrest. Sensitizes cells to ionizing radiations and chemotherapeutics. Induces apoptosis in breast and prostate cancer cell lines. 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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