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4-METHYL-N-[3-(4-METHYL-1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL)PHENYL]-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]-BENZAMIDE

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  • SKU: N-2364-INQUIRE
  • Pack Size: INQUIRE
4-METHYL-N-[3-(4-METHYL-1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL)PHENYL]-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]-BENZAMIDE

641571-10-0

529.52

C28H22F3N7O

DMSO (50 mg/ml)

-20°C


 A potent, selective BCR-ABL inhibitor that fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib (Cat. No. 1625-100, 1000). Nilotinib is not only more potent than imatinib against wild-type BCR-ABL (IC< 30 nM), but also significantly active against 32/33 imatinib-resistant BCR-ABL mutants.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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