Soluble in DMSO (5mg/ml), acetone or ethyl acetate; insoluble in dichloromethane.
Synonyms: Tyrphostin AG 1112; (5Z)-3-AMINO-5-[(2Z)-1-CYANO-2-INDOL-3-YLIDENEETHYLIDENE]-1,2-DIHYDROPYRAZOLE-4-CARBONITRILE
AG 1112 also known as Tyrphostin AG 1112 is a Casein Kinase II inhibitor. It is a Bcr-Abl Kinase blocker that stimulates and activates the terminal differentiation of K562 cells and the purging of Ph+ cells. AG 1112 has been suggested to be regulatory in function, some of them are cell proliferation, cell differentiation, and apoptosis.
Research or further manufacturing use only, not for food or drug use.