425.4
C15H13F2N7O2S2
Soluble in DMSO (10mg/ml).
-20°C
Cell permeable triazolo-diamine compound;displays anti-proliferative properties inhuman cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3 (IC=32nM and 140nM).
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
