May be dissolved in DMSO (20 mg/mL) or water (2 mg/mL)
Originally isolated from a marine sponge, Fascaplysin is selective CYCLIN-DEPENDENT KINASE 4 INHIBITOR (in a ATP competitive manner). Selective CDK4/cyclin D1 (IC50 = 350 nM) inhibitor (in an ATP competitive manner).
Fascaplysin is an inhibitor of Cdk6. Fascaplysin exert anti-tumor effects through apoptotic and anti-angiogenesis pathways. Fascaplysin has recently been shown to be a DNA intercalator.
Not for human therapeutic use or for medicinal purposes. For research applications only.
Research or further manufacturing use only, not for food or drug use.