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R-(R)-Roscovitine, selective CDK Inhibitor, 50 MG

Price$ 542.72
  • SKU: R-1016-50MG
  • Pack Size: 50 MG
Quantity
-
+

186692-46-6

354.5

C19H26N6O

Soluble in chloroform (50mg/ml), ethanol or warm DMSO @ (10mg/ml), or methanol; moderately soluble in water.

-20°C


Potent and selective inhibitor of cyclin-dependent kinases (cdks). Selective for CDK1, CDK2, and CDK5.A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma.Glycogen Synthase Kinase-3 Plays a Central Role in Mediating Glucocorticoid-Induced Apoptosis.Dying and Necrotic Neutrophils Are Anti-Inflammatory Secondary to the Release of -Defensins.Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages.Pkd1 and Nek8 mutations affect cell-cell adhesion and cilia in cysts formed in kidney organ cultures.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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