3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
280744-09-4
371.2
C19H12Cl2N2O2
DMF, DMSO
-20°C
SB-216763 is a potent, cell-permeable and ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) (K= 9 nM for GSK-3). Has little activity against 24 other protein kinases (IC 10M). Stimulates glycogen synthesis, gene transcription and is neuroprotective.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.