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Price$ 645.24
  • SKU: S-2446-25MG
  • Pack Size: 25 MG
Quantity
-
+

658084-23-2

568.09

C28H30ClN5O4S

DMSO (~ 10 mg/ml on warming)

-20°C


A specific, ATP-competitive small molecule inhibitor of the catalytic activity of Met. Displays selectivity for Met enzyme versus a panel of other tyrosine kinases with the following ICvalues: Met = 0.02M, Flk = 1.3M, EGFR = >100M, PDGFR = >20M, Tie2 = >100M, c-src = >10M, cdk2 = >10M, and FGFR-1 = 9.7M). Inhibition of the Met kinase activity by SU11274 leads to time- and dose-dependent reduced cell growth and induced G1 cell cycle arrest and apoptosis.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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