105628-07-7
327.83
C14H17N3O2S•HCl
Soluble in Water (175 mg/ml) or DMSO (10 mg/ml)
-20°C
A cell-permeable Ca²⁺ antagonist and vasodilator. Inhibits protein kinase A (Ki = 1.6 µM), protein kinase G (Ki = 1.6 µM), myosin light chain kinase (Ki = 36 µM) and Rho kinase (ROCK; IC50 = 10.7 µM. Fasudil also mobilizes adult neural stem cells in vivo.
0.1 lbs
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