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Bisindolylmaleimide IX methanesulfonate, 5 MG

Price$ 343.72
  • SKU: R-2418-5MG
  • Pack Size: 5 MG
Quantity
-
+

138489-18-6

553.65

C25H23N5O2S.CH4O3S

DMSO (~ 100 mg/ml) or water (~ 5 mg/ml)

-20°C


Cell-permeable. A potent bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively). It inhibits protein kinase A (PKA) (IC50 = 0.9 μM) and calcium/calmodulin kinase II (IC50 = 17 μM) at much higher concentrations. Also inhibits glycogen synthase kinase-3 (GSK-3) (IC50 = 6.8 nM).

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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