trans-4-[(1R)-1-aminoethyl]-N-4-pyridinyl-Cyclohexanecarboxamide, dihydrochloride
129830-38-2
320.3
C14H21N3O • 2HCl
Water, DMSO, PBS (pH 7.2)
-20°C
Y-27632 Dihydrochloride is a potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor.
Prevents apoptosis and enhances the survival and cloning efficiency of dissociated human embryonic stem (hES) cells without affecting their pluripotency. Increases survival rate of hES cells undergoing cryopreservation.
Contains approx. 1.4% water.
Applications:
• Tumor cell invasion and metastasis suppressor.
• Smooth muscle relaxant.
• Decreases liver fibrosis by hepatic stellate cell growth inhibition.
• Antinociceptive.
• Blocks generation of inflammatory cytokines.
• Stem cell research modulator.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
