108605-62-5
270.21
C12H9F3N2O2
DMSO
-20°C
A77 1726 physiologically active metabolite of the immunosuppressive drug leflunomide (Cat. No.1972-10, 50). A77 1726 Inhibits the activity of dihydroorotate dehydrogenase and of protein tyrosine kinases. A77 1726 Blocks TNF-mediated NF-κB activation in a dose- and time-dependent manner. A77 1726 Also inhibits the activity of COX-2 in vitro and in vivo.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
