Soluble in DMSO and Ethanol.
AG 879 or Tyrphostin AG 879 inhibits the tyrosine kinase activity of nerve growth factor(NGF)-dependent TrKA tyrosine phosphorylation in in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM). It acts as an antiproliferative agent for diseases caused by the hyperactivity of PTKs. AG-
Research or further manufacturing use only, not for food or drug use.