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Price$ 103.30
  • SKU: A-1198-5MG
  • Pack Size: 5 MG
Quantity
-
+

148741-30-4

316.5

C18H24N2OS

Soluble in DMSO and Ethanol.

-20°C


AG 879 or Tyrphostin AG 879 inhibits the tyrosine kinase activity of nerve growth factor(NGF)-dependent TrKA tyrosine phosphorylation in in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM).  It  acts as an antiproliferative agent for diseases caused by the hyperactivity of PTKs. AG-879 has also been shown to suppress IL-6-induced tyrosine phosphorylation of STAT3 (IC50 = 15 μM) in schwannoma cells.

 

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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