2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-3-pyridinecarboxamide, monohydrochloride
1615197-10-8
426.9
C20H18N6O3 • HCl
DMSO
-20°C
Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC= 10 nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7 M. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
