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Imatinib mesylate, 1 G

Price$ 391.50
  • SKU: I-2359-1GM
  • Pack Size: 1 G
Quantity
-
+

220127-57-1

589.71

C29H31N7O.CH4SO3

DMSO (100 mg/ml)

-20°C


An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC= 0.5 nM), phosphorylation of a fusion protein (IC= 30 nM), and viability of BaF3 cells expressing Rhe-PDGFR in the absence of IL-3 (IC= 0.17 nM).

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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