219580-11-7
523.67
C28H41N7O3
Soluble in DMSO (10 mg/ml)
-20°C
A potent and selective FGFR1 tyrosine kinase inhibitor (IC= 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.