249762-74-1
346.4
C21H18N2O3
DMSO
+2-8°C
A cell permeable bis(1H-2-indolyl)-1-methanone compound that acts as a highly selective, ATP-competitive and reversible inhibitor of platelet-derived growth factor receptor tyrosine kinase. Also potently inhibits Flt3 activity. Sensitzes 32D cells to radiation-induced apoptosis and inhibits prliferation of TEL-Flt3-transfected BA-F3 cells. May also serce as a prodrug for of the PDGF Receptor Tyrosine Kinase Inhibitor I in cells.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
