Soluble in DMSO (up to 20 mg/ml).
2'-Deoxy-5-fluorocytidine is a DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors. Like 5'-Azacytidine and decitabine, 2-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo.
Research or further manufacturing use only, not for food or drug use.